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  • https://support.waters.com/KB_Inst/Chromatography/WKB21227_What_is_the_part_number_for_the_48_well_2mL_Acquity_vial_holder_plate_label_that_is_found_in_the_Acquity_Sample_Manager_Startup_Kit
    ANSWER: 615003783 Label 48 Well, 2mL Vial Open Access
  • https://support.waters.com/KB_Inst/Chromatography/WKB196173_Negative_leak_rate_for_primary_when_running_dynamic_leak_test_-_ACQUITY
    SYMPTOMS: Successful dynamic leak test Primary pump head passes dynamic leak test with negative leak rate values Primary pump head occasionally passes with acceptable leak rate values Increase of leak...SYMPTOMS: Successful dynamic leak test Primary pump head passes dynamic leak test with negative leak rate values Primary pump head occasionally passes with acceptable leak rate values Increase of leak rate on accumulator seen when leak rate on primary is monitored Seals and check valves are new, replaced more than once on both primary and accumulator pumps CAUSE: Faulty primary pump head FIX: Replace the primary pump head. Perform the dynamic leak test.
  • https://support.waters.com/KB_Inst/Chromatography/WKB11277_How_much_sample_is_consumed_using_the_partial_loop_with_needle_overfill_injection_mode_on_the_ACQUITY_UPLC_Sample_Manager
    ANSWER: The specified injection volume plus 15.0 µL (14.0-µL pre-sample volume and 1.0-µL post sample volume) when using the default setting of "automatic". The default overfill volume changes with re...ANSWER: The specified injection volume plus 15.0 µL (14.0-µL pre-sample volume and 1.0-µL post sample volume) when using the default setting of "automatic". The default overfill volume changes with respect to the needle configured: Advanced setting selected as "automatic" 10 ul needle (7.0µL pre-sample volume and 1.0µL post sample volume) 20 ul needle (10.0µL pre-sample volume and 1.0µL post sample volume)
  • https://support.waters.com/KB_Inst/Chromatography/WKB244210_BSM_Pressure_Fluctuations_Observed
    SYMPTOMS: Erratic BSM pressure trace No flow from vent line during priming CAUSE: Solvent bottle filter clogged FIX: Replace the solvent bottle filter.
  • https://support.waters.com/KB_Inst/Chromatography/WKB224123_Split_peaks_and_contamination_peaks_in_blanks
    SYMPTOMS: Split/broad peaks on samples Peaks on blanks Replaced/investigated all possible parts/areas of contamination on LC modules (BSM, SM, CM/CH, column and MS) CAUSE: Contaminated mobile phases F...SYMPTOMS: Split/broad peaks on samples Peaks on blanks Replaced/investigated all possible parts/areas of contamination on LC modules (BSM, SM, CM/CH, column and MS) CAUSE: Contaminated mobile phases FIX: Make up fresh mobile phase using new solvents and additives where possible. Ensure that you are not using contaminated source of additive and/or solvent.
  • https://support.waters.com/KB_Inst/Chromatography/WKB224229_Rising_backpressure_high_delta_on_BSM
    SYMPTOMS: Rising back pressure; pressure drops in cycles and increases again High delta on ACQUITY BSM CAUSE: Partially clogged column FIX: Replace the problematic column in the column compartment.
  • https://support.waters.com/KB_Inst/Chromatography/WKB101611_Customer_reports_low_sensitivty_or_no_peaks_at_certan_points
    SYMPTOMS: Low sensitivity No peaks Incorrect retention time Strange baseline CAUSE: Old or wrong chemistry FIX: Use a freshly prepared sample. Use a fresh column. Use a fresh precolumn / filter. Use f...SYMPTOMS: Low sensitivity No peaks Incorrect retention time Strange baseline CAUSE: Old or wrong chemistry FIX: Use a freshly prepared sample. Use a fresh column. Use a fresh precolumn / filter. Use freshly prepared mobile phases and wash solutions. Use the correct Method and solvents.
  • https://support.waters.com/KB_Inst/Chromatography/WKB5510_What_is_the_part_number_for_the_puncture_needle_in_the_ACQUITY_UPLC_Sample_Manager
    ANSWER: Extended Y-Carriage implemented on all Sample Managers manufactured in January 2008 beginning with serial numbers. A08UPA918M for the ACQUITY Sample Manager and A08NPS351M for the nanoACQUITY ...ANSWER: Extended Y-Carriage implemented on all Sample Managers manufactured in January 2008 beginning with serial numbers. A08UPA918M for the ACQUITY Sample Manager and A08NPS351M for the nanoACQUITY Sample Manager Extended Y-Carriage is identified by a gray or stainless steel knob that holds the needle loop 700003898 for the PUNCTURE NEEDLE CART, 12MM EFF.MECHANISM 700006067 for the I-Class SM-FL and the M-Class SM-FL For any Sample Managers which have older versions of Y carriage, it is necess
  • https://support.waters.com/KB_Inst/Chromatography/WKB11161_What_is_the_part_number_of_the_tray_that_holds_the_vial_holders_in_Classic_ACQUITY_UPLC_Sample_Manager
    ANSWER: KIT, WELLPLATE SHUTTLE - 205000542
  • https://support.waters.com/KB_Inst/Chromatography/WKB1378_What_is_the_part_number_for_the_fan_on_the_back_of_the_ACQUITY_UPLC_Sample_Managers_heater_cooler_engine
    ANSWER: 700004626: 24 V fan assembly (engineering code 279000824 )
  • https://support.waters.com/KB_Inst/Chromatography/WKB19653_What_is_the_part_number_for_the_ACQUITY_Sample_Manager_pressure_transducer
    ANSWER: 700002650 - Pressure transducer