Troubleshooting LockSpray signal issues on QTofs and Tofs with IntelliStart (Guided Troubleshooting) - WKB96098

SYMPTOMS

• Signal issues via reference probe
• No signal
• Low signal intensity
• Unstable signal
• Delayed flow/signal
• Decaying signal

ENVIRONMENT

• Xevo QTof
• Xevo G2 
• Xevo G2-S
• Xevo G2-XS
• SYNAPT G2
• SYNAPT G2-S
• SYNAPT G2-Si
• IntelliStart

STRATEGY

1. Use higher flow rate - WKB13748
2. Ensure that orange fluidics tubing is fully submerged in the wash solution - WKB69940
3. Most Likely:  Purge reference fluidics (at least 5 times) - WKB92145
4. Tighten PEEK nut at end of the reference probe mount assembly - WKB57869
5. Trim the end of or replace the tubing from reservoir B to the reference valve - WKB51661
6. Use a more aqueous LockSpray solution - WKB13748
7. Rebuild reference probe - WKB6834
8. Purge syringe pump and blue tubing directly with methanol - WKB67224

ADDITIONAL INFORMATION