Poor resolution on Tof mass spectrometers (Guided Troubleshooting) - WKB95206

SYMPTOMS

Resolution on GFP standard at 0.1 IPP is below specifications, but peaks are stable.

ENVIRONMENT

• Xevo QTof
• Xevo G2 QTof
• Xevo G2-S
• Xevo G2-XS
• SYNAPT HDMS
• SYNAPT G2-S 
• SYNAPT G2-Si
• Vion IMS QTof
• ACQUITY RDa Detector
• BioAccord System

STRATEGY

1. In case of intact protein analysis, confirm vacuum levels - WKB45630.
2. Consider restoring last known good settings from EPC or target registry backup (back up current target registry using TREG editor first in case restored settings are even worse) - WKB64379.

ADDITIONAL INFORMATION