Unstable pressure on ACQUITY UPLC - WKB22900

SYMPTOMS

• Pressure is unstable
• Dynamic leak test pass
• Sonicating the check valves does not resolve issue
• Primary pressure trace displays little to no pressure difference on each stroke (see picture)
  

ENVIRONMENT

• ACQUITY UPLC H-Class
• ACQUITY UPLC H-Class Bio
• ACQUITY Quaternary Solvent Manager (QSM)
• ACQUITY UPLC M-Class
• ACQUITY Premier

CAUSE

Faulty primary i2v check valve

FIX or WORKAROUND

1. Replace the check valve. Click HERE for detailed steps and a video showing check valve replacement. 
    
2. 

ADDITIONAL INFORMATION

Part Numbers:

For H-Class: 700005165, i2 Valve Cartridge

For H-Class Bio: 700005414, Cartridge, i2V, BioACQUITY

For M-Class: 700005414, Cartridge, i2V, BioACQUITY

For more options see Graphical Parts Locator

Other articles related to this issue:

1. High pressure fluctuations on ACQUITY H-Class QSM - WKB55705
2. Pressure fluctuations on ACQUITY UPLC H-Class QSM after PM - WKB28335
3. Pressure fluctuations on ACQUITY H-Class QSM - WKB19400
4. Pressure fluctuations on ACQUITY UPLC H-Class QSM - WKB21289
5. ACQUITY H-Class QSM pressure drops - WKB9737