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ACQUITY H-Class QSM pressure drops - WKB9737

Article number: 9737

SYMPTOMS

  • Pressure remains stable using each channel individually
  • When mixing several channels, C/D ratio starts to increase, until pressure starts dropping

ENVIRONMENT

  • ACQUITY UPLC H-Class
  • ACQUITY UPLC H-Class Bio
  • QSM

CAUSE

Kinked or blocked degasser tubing

FIX or WORKAROUND

  1. Inspect the degasser tubing.
  2. Reroute the tubing as necessary.

ADDITIONAL INFORMATION

See service note: QSM, Bio QSM: Ensure degasser vacuum tubing is not kinked. Could cause intermittent peak shifts and pressure dropouts.

Other articles related to this issue:

  1. High pressure fluctuations on ACQUITY H-Class QSM - WKB55705
  2. Pressure fluctuations on ACQUITY UPLC H-Class QSM after PM - WKB28335
  3. Pressure fluctuations on ACQUITY H-Class QSM - WKB19400
  4. Pressure fluctuations on ACQUITY UPLC H-Class QSM - WKB21289
  5. Pressure fluctuation on ACQUITY solvent manager - WKB21265

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