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What is the latest version of MassLynx for desktop or post-processing? - WKB5817

Article number: 5817

ENVIRONMENT

  • MassLynx
  • MassLynx Desktop
  • Windows 10

ANSWER

Note: to use MassLynx for processing only - select "no instrument" when installing the MassLynx software

Latest Full Install Version Release date Windows Operating System Supported

MassLynx 4.2 SCN 1051

November 2025 Windows 11 Enterprise LTSC 2024 (64-bit) [Waters Lenovo P5 6 Core only],
Windows 10 Enterprise LTSC 2021 (64-bit) [Waters Lenovo P5 6 core, P5 12 Core and P520 only],

Click links for release notes.

Note: it is highly recommended to use a dedicated PC for processing data, and another for data acquisition.

ADDITIONAL INFORMATION

In MassLynx, do you get media with the purchase of a supplemental license? - wkb122210

Is there a standalone version of TargetLynx Browser? - wkb95242

Also see How to request a MassLynx software upgrade

For MS instrument control, see the article What is the latest version of MassLynx SCN that supports my MS instrument?

Previous Full Install Versions Release date Windows Operating System Supported
MassLynx 4.2 SCN 1050
June 2025 Windows 11 Enterprise LTSC 2024 (64-bit) [Waters Lenovo P5 6 Core only],
Windows 10 Enterprise LTSC 2021 (64-bit) [Waters Lenovo P5 6 core, P5 12 Core and P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1049
October 2024 Windows 10 Enterprise LTSC 2021 (64-bit), [Waters Lenovo P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1048
July 2024 Windows 10 Enterprise LTSC 2021 (64-bit), [Waters Lenovo P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1046
March 2024 Windows 10 Enterprise LTSC 2021 (64-bit), [Waters Lenovo P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1045 July 2023 Windows 10 Enterprise LTSC 2021 (64-bit), [Waters Lenovo P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1043 February 2023 Windows 10 Enterprise LTSC 2021 (64-bit), [Waters Lenovo P520 only],
Windows 10 Enterprise LTSB 1607
MassLynx 4.2 SCN 1035 March 2022 Windows 10 Enterprise LTSB 1607

MassLynx 4.2 SCN 997
(Processing only for data acquired from Xevo TQ-XS, Xevo TQ-S micro, Xevo TQ-S cronos, and the Xevo TQD)

May 2021 Windows 10 Enterprise LTSB 1607
Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.2 SCN 1012
For all other instrument data
May 2021 Windows 10 Enterprise LTSB 1607
Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.2 SCN 1007 September 2019 Windows 10 Enterprise LTSB 1607
Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.2 SCN 982 September 2017 Windows 10 Enterprise LTSB 1607
Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.2 SCN 943 June 2016 Windows 7 Professional 64 Bit, Service Pack 1

MassLynx 4.1 SCN 909 :

(Note - this is the first MassLynx SCN in which Metabolynx is tolerant of the latest versions of Java)

October 2014 Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.1 SCN 918 July 2014 Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.1 SCN 901   October 2013 Windows 7 Professional 64 Bit, Service Pack 1
MassLynx 4.1 SCN 871 December 2011 Windows 7 Professional 64 Bit, Service Pack 1NOTE: From

MassLynx 4.1 SCN851 onwards the Synapt G2-S/Si instrument control SCNs use some data compression of MSe data. MassLynx 4.1 SCN 871 is the earliest SCN that can process MSe data acquired with SCN 851 and later

  

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