- MS scan detects the spectrum of the target compound cleavage.
- Synapt G2-S
- Synapt G2-Si
- Xevo G2-S
- Xevo G2-XS
It collides with the argon gas filled in the collision cell and decays.
FIX or WORKAROUND
When Collision Enegy in MS Method is set to Off, a 6V collision voltage is applied.
As shown in the figure below, after setting Collision Energy to On, enter a value smaller than 6V (eg. 3V).
If the problem persists, see the following article.
The following ions tend to undergo in-source decay.
– Ions less than m/z 300
– Ions with high valence
– Ions with unstable structure