High RSD on Xevo TQ-XS in combination with APGC - WKB68661

SYMPTOMS

• When running a long sequence of the same sample (more than 20 injections), the RSD is over 10%

ENVIRONMENT

• Xevo TQ-XS
• APGC
• CTC PAL

CAUSE

When tuning on the column bleeding peak (m/z 207), the beam intensity is unstable.

The CTC PAL autosampler syringe does not enter the middle of the injection port septa.

FIX or WORKAROUND

1. Adjust the Aux gas flow until the bleeding peak is stable.
2. Check the injector parameters of the CTC and adjust the position is needed.

ADDITIONAL INFORMATION