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For running the mass spectrometer at high flow rates, what are recommended flow rates versus temperature and gas flow? - WKB204351

Article number: 204351

ENVIRONMENT

  • Mass spectrometer
  • MassLynx
  • UNIFI
  • Xevo TQ MS
  • Xevo TQD
  • Xevo TQ-S
  • Xevo TQ-S cronos
  • Xevo TQ-S micro
  • Xevo TQ-XS

ANSWER

When optimizing desolvation and thus sensitivity, appropriate gas flows and desolvation temperatures are needed.

Find information in the Operators Overview and Maintenance Guide for each particular instrument in the Waters Support Library. This information is also in the MassLynx Help file.

For example:

Xevo TQ-XS Mass Spectrometry - Overview and Maintenance Guide:

clipboard_eff0f15da816ef83d0962235223cb91fb.png

ADDITIONAL INFORMATION

At higher flow rates, capillary voltage may need to be reduced and probe position may need to be adjusted away from the cone. Notice: If you position the probe too close to the sample cone, nonlinear data, sample suppression, and the need for frequent source cleaning can result. 

Re-optimizing the ESI probe position - WKB79485

How to optimize for either ESI or APcI using ESCI with intellistart - WKB9654

How to tune up for APCI or ESCI mode - WKB7804 

id204351, Electrospray, MLYNX, MLYNXV41, SUPMM, SUPUNIFI, UNIFISVR, UNIFISW18, UNIFOPT, UNIFQLIC, UNIFSW17, UNIFSW18, UNIFSW19, UNIFWGLIC, UNIFWKLIC, XEVOG2XSQT, XEVOTQ, XEVOTQD, XEVOTQDIVD, XEVOTQIVD, XEVOTQS, XEVOTQSCRO, XEVOTQSIVD, XEVOTQSMIC, XEVOTQXS, XEVTQSMIVD, XEVTQXSIVD

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