No calibrant signal using the fluidics on Xevo G2-XS - WKB19810

SYMPTOMS

• Purged three times and pumped for 15 minutes, but still no calibrant signal
• Calibrant in reservoir C pumping through the sample fluidics - no signal

ENVIRONMENT

• SYNAPT G2
• SYNAPT G2-S
• SYNAPT G2-Si
• Vion IMS QTof
• Xevo QTof
• Xevo Tof
• Xevo G2 QTof
• Xevo G2 Tof
• Xevo G2-S
• Xevo G2-XS
• Xevo G3

CAUSE

The wash line is not submerged in the wash solution. The pump uses wash solution to move/push the sample solution through the lines.

FIX or WORKAROUND

• Identify the orange wash lines that go out of the fluidics to a wash bottle that is either on top of the MS or on top of the LC.
• Ensure that the orange line is submerged in the wash solution. If it keeps popping out, unscrew the solvent bottle lid with the line still in it and feed a pre-slit vial cap over the line, all the way up to the lid. This will help the line stay in position.

ADDITIONAL INFORMATION