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High delta psi and pressure unstable with e2695 Separations Module - WKB25194

Article number: 25194

SYMPTOMS

  • High delta psi
  • Pressure fluctuation
  • Erratic pressure

ENVIRONMENT

  • Alliance HPLC System
  • 2695 Separations Module

CAUSE

Stroke volume is not optimized for flow rate (set to default).

FIX or WORKAROUND

  1. Set the stroke volume to a lower value, as illustrated in the chart below.

Flow range (mL/min) Stroke volume (µL)
0.050 - 0530 25
0.531 - 1.230 50
1.231 - 3.030 100
3.031 - 5.00 130

 2. The stroke volume can be set in method parameters in Empower or on the front panel of the Alliance HPLC system. See WKB45439.

ADDITIONAL INFORMATION

Find details on how to set the stroke volume on the Alliance HPLC system in the 2695 Separations Module Operating Guide.

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