Reduced peak sensitivity for drug material standards on SQD - WKB60930
Article number: 60930
SYMPTOMS
- Peak areas of standard peaks reduce or drop in intensity over many assays
- Cleaning cone partially brings back signal
ENVIRONMENT
- ACQUITY SQD
- ACQUITY TQD
- Xevo TQD
- Xevo TQMS
- Xevo TQS
CAUSE
Dirty ESI probe capillary
FIX or WORKAROUND
Rebuild or replace the ESI probe.
ADDITIONAL INFORMATION
id60930, A-SQ, A-SQ, Electrospray, SQD, SQD2, TQD, TQDIVD, XEVOTQD, XEVOTQDIVD