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Ion energies are optimizing at highly negative values (-1.5 to -5.0 V) for a triple-quadrudole mass spectrometer - WKB30577

Article number: 30577

SYMPTOMS

  • Ion Energy (IE) values are optimizing at highly negative values (-1.5 to -5.0 V) in both positive and negative modes on a triple-quad mass spectrometer 
  • Sometimes a 59 Da peak is present in the spectra

ENVIRONMENT

  • Triple-quadrupole mass spectrometers
  • Xevo TQD
  • Xevo TQ-S
  • Xevo TQ-S Micro
  • Xevo TQ-XS

CAUSE

Potential causes:

  • Suboptimal capillary position within the probe
  • The ion guide or prefilter is dirty or has a fault
  • The ion guide is not seated correctly and is making full contact internally such that it is not fully grounded
  • The ion guide feed-through cable is not seated correctly or has a fault

FIX or WORKAROUND

  1. Check the capillary position within the probe.
  2. Clean the ion guide or prefilter.
  3. Reseat the ion guide.
  4. Inspect the ion guide feed-through cable.
  5. Replace the ion guide and prefilter.

ADDITIONAL INFORMATION

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