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Low points per peak and poor chromatography peak shape in MassLynx - WKB28711

Article number: 28711

SYMPTOMS

  • Chromatography is unsatisfactory with poor peak shape - broad peaks. 
  • When creating MS Method the Points Per Peak is lower than it should be - half compared to a working system. 
    For example: Peak width = 4 and Required Points Per Peak = 12.
  • Cannot achieve 15 points per peak even though the dwell time was adjusted to the lowest possible setting in the MS method.
  • Has been seen after a PM visit or Installation visit.

ENVIRONMENT

  • Xevo TQ-S
  • Xevo TQ-XS
  • MassLynx
  • TargetLynx

CAUSE

Inter-Scan Setup was set to Manual mode. 

FIX or WORKAROUND

  1. Disable Manual Inter-Scan Delay setting on the tune page (Tune page> Setup >Inter-Scan Setup) and ensure that "Enable Manual Mode" is NOT selected.

ADDITIONAL INFORMATION

During a PM, for the charging test in some instruments, the Inter-scan Setup is set to manual. If this value is not reset this issue can occur. Same problem can be encountered after an Installation visit. 

id28711, MLYNX, MLYNXV41, SUPMM, TARLYNX41, XEVOG2XSQT, XEVOTQS, XEVOTQSIVD, XEVOTQXS, XEVTQSMIVD, XEVTQXSIVD

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