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Can I use an ACQUITY QDa instead of a Xevo TQ-S micro for application note 720007545 (Enhanced Performance of the Analysis for Veterinary Drugs with Metal Affinity Using ACQUITY Premier)? - WKB232707

Article number: 232707

ENVIRONMENT

  • Veterinary drugs
  • Application note
  • ACQUITY QDa
  • Xevo TQ-S micro

ANSWER

It might be possible, but see the "Additional Information" section.

ADDITIONAL INFORMATION

Waters has not evaluated an ACQUITY QDa for this method.  

The sensitivity may be 10 to 50 times lower when running a QDa. This is because the QDa uses Selected Ion Recording (SIR) whereas the Xevo TQ-S micro uses Multiple Reaction Monitoring (MRM). 

Link to application note: 

Enhanced Performance of the Analysis for Veterinary Drugs with Metal Affinity Using ACQUITY™ Premier and Xevo™ TQ-S Micro

id232707, QDA, XEVOTQSMIC

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