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Waters

QDa has low sensitivity - WKB225823

Article number: 225823

SYMPTOMS

  • 30% loss of sensitivity
  • Loss is random among all samples
  • For most samples, chromatogram peak shape is "spiky"

ENVIRONMENT

  • ACQUITY QDa Mass Detector
  • BioAccord System
  • ACQUITY RDa Detector

CAUSE

Bad ESI probe spray and ionization 

FIX or WORKAROUND

Replace the ESI probe.

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