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Waters

What Milli-Q or water purification systems are used in Waters labs? - WKB191699

Article number: 191699

ENVIRONMENT

  • Milli-Q
  • Water purification
  • LC-MS solvents

ANSWER

ADDITIONAL INFORMATION

  • Ultra‐pure water is sterile and contains no particles greater than 0.2 microns, no detectable ionizable compounds (>18 MegaOhm (MΩ).cm resistivity), and low UV absorbance at the monitoring wavelengths.
  • Use of ultra‐pure water reduces the number of impurities in the water that can collect on the column during equilibration with the weak solvent.
  • Ultra‐pure water is sterile and contains no particulates, no detectable ionizable compounds, and no UV‐absorbing compounds. The purification process must include all of the following steps:
    • a. Reverse osmosis (to remove most contaminants)
      b. UV sterilization (to kill bacteria)
      c. Ion exchange (to remove any remaining ions)
      d. Carbon filtration (to remove any remaining ionizable compounds)
      e. A pharmaceutical‐grade 0.2‐micron membrane filter (to remove any remaining particulates)

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