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Baseline noise during gradient analysis using TFA in ACQUITY UPLC and I-Class - WKB90863

Article number: 90863

SYMPTOMS

  • In BSM, baseline noise occurs irregularly during gradient analysis using a mobile phase containing TFA
  • Poor noise reproducibility
  • The pressure is stable

ENVIRONMENT

  • ACQUITY UPLC
  • ACQUITY UPLC I-Class
  • BSM

CAUSE

Mixing failure in the mixer

FIX or WORKAROUND

Replace the mixer.

ADDITIONAL INFORMATION

 

 

id90863, baseline ripple, eluent, UPBINARY, UPBINARY, UPBSM+, UPIBSM, UPIBSM, UPIBSM+, UPIBSM+, UPISMFL, UPISMFL+, UPISMFTIVD, UPISMFTN, UPISMFTN+, UPPBSM

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