Negative peaks observed using Refractive Index Detector - WKB67342
Article number: 67342
SYMPTOMS
- Negative peaks observed using Refractive Index Detector
- Negative peaks have the same peak shape and intensity as positive peaks, but they appear mirrored
- Reduce back pressure does not resolve
- Occurring in both standard and samples
- Noise and drift test pass, but peak integration is not consistent.
ENVIRONMENT
- 2410 Differential Refractometer
- 2414 Refractive Index Detector
- ACQUITY RI Detector
CAUSE
The cell is dirty
FIX or WORKAROUND
- Clean the sample and reference cell as described in the Refractive Index Detector Overview and Maintenance Guide. See the section "Decontaminating the fluidics path".
ADDITIONAL INFORMATION
If this does not resolve see Dip in 2414 baseline - WKB200978
id67342, 2410, 2414, 2414B, A-10RI, A-30RI, UPRI, UPRIARC