Classic ACQUITY Sample Manager error: Sample pressure low; possibly no wash solvent or needle damaged - WKB60404

SYMPTOMS

• Error message in console: "Sample pressure low; possibly no wash solvent or needle damaged"

ENVIRONMENT

• ACQUITY UPLC Sample Manager 

CAUSE

Blockage or damage to needle

FIX or WORKAROUND

1. Replace the sample needle.
2. Calibrate the XYZ mechanism following the procedure in section 2-67 of the user's guide.
3. Calibrate the needle z axis following the procedure in section 6-139 of the user's guide.
4. Characterize the needle seal and the needle and sample loop volumes following the procedure in section 6-140 of the user's guide.
5. Ensure that the sample manager can successfully perform injections.

ADDITIONAL INFORMATION