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System overpressure error - WKB60378

Article number: 60378

SYMPTOMS

  • System overpressure error is triggered even at very low flow rate
  • System pressure is normal when the column is replaced by a union

ENVIRONMENT

  • Alliance HPLC System
  • 2695 Separations Module
  • 2695D Dissolution Separations Module
  • 2795 Separations Module
  • ACQUITY UPLC Binary Solvent Manager 
  • ACQUITY UPLC H-Class Binary Solvent Manager 
  • ACQUITY UPLC H-Class Quaternary Solvent Manager
  • ACQUITY UPLC I-Class Binary Solvent Manager 
  • ACQUITY UPLC I-Class PLUS Binary Solvent Manager 
  • ACQUITY UPLC Columns

CAUSE

The column and/or pre-filter/guard column is either partially or completely clogged.

FIX or WORKAROUND

Replace the pre-filter/guard and/or column.

ADDITIONAL INFORMATION

 

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