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ACQUITY UPLC FLR detector error: Improper Flow Cell Contents Possible - WKB46725

Article number: 46725

SYMPTOMS

  • Instrument does not initialize
  • "Improper Flow Cell Contents Possible" error appears during startup

ENVIRONMENT

  • ACQUITY UPLC FLR Detector
  • ACQUITY UPLC

CAUSE

Contaminants in the flow cell

FIX or WORKAROUND

  1. Power-off the FLR.
  2. Replace the column with a union, or put Column Manager in Bypass.
  3. Flow 1:1:1:1 methanol/water/isopropanol/acetonitrile through the flow cell at 0.2 mL/min for a few hours (overnight if possible).
  4. Flush the flow cell with 100% water at 0.2 mL/min for an hour.
  5. Power-on the FLR.

ADDITIONAL INFORMATION

 

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