- Instrument does not initialize
- "Improper Flow Cell Contents Possible" error appears during startup
- ACQUITY UPLC FLR Detector
- ACQUITY UPLC
Contaminants in the flow cell
FIX or WORKAROUND
- Power-off the FLR.
- Replace the column with a union, or put Column Manager in Bypass.
- Flow 1:1:1:1 methanol/water/isopropanol/acetonitrile through the flow cell at 0.2 mL/min for a few hours (overnight if possible).
- Flush the flow cell with 100% water at 0.2 mL/min for an hour.
- Power-on the FLR.