System pressure on an Alliance drops and then recovers - WKB226020
Article number: 226020
SYMPTOMS
- System pressure drops, often to 0 psi, and then recovers
- The pressure drops occur at high pressure
- RT shift is observed when running sample
- May also cause baseline issue
ENVIRONMENT
- Alliance HPLC System
- 2695 Separations Module
- 2695D Dissolution Separations Module
- 2795 Separations Module
CAUSE
Contaminated/bad check valve
FIX or WORKAROUND
- Clean or replace the check valves. Part number: 700000254 - PerformancePLUS™Check Valve Cartridges
- Verify functionality by performing pressure test with stable delta
