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Waters

Baseline slowly drifting on the 2414 Refractive Index (RI) Detector - WKB11406

Article number: 11406

SYMPTOMS

  • Baseline is very slowly drifting down
  • Instrument was powered-on overnight
  • Sample and reference flow cell thoroughly purged
  • LED optimized
  • New mobile phase
  • Very low pump pressure ripple
  • New assay
  • Flow rate accurate

CAUSE

Temperature was set on the column, but not on the detector.

FIX or WORKAROUND

  1. Set detector temperature.

ADDITIONAL INFORMATION

2414 Refractive Index Detector Overview and Maintenance Guide

eluent, pressure fluctuation

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