TargetLynx does not integrate some of the peaks in the method - WKB2423

SYMPTOMS

• Chromatographic peaks for compounds of interest are not integrated
• Chromatographic peak for labeled internal standard is integrated
• Both compounds elute at the same time.
• The retention time for compounds of interest set in the method differs from the retention time of the peak in the chromatogram

ENVIRONMENT

• MassLynx 4.1
• TargetLynx 4.1

CAUSE

The predicted retention time for the compound of interest is incorrect in the TargetLynx method.

FIX or WORKAROUND

1. Change the Predicted Retention Time value in the TargetLynx method to the correct retention time for the peak of interest.
2. Reprocess the data from the sample list.

ADDITIONAL INFORMATION