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"Internal Error: Reset communications from control menu" appears when starting Sample Tune and Develop Method in IntelliStart - WKB11452

Article number: 11452

SYMPTOMS

  • "Internal Error: Reset communications from control menu"
  • Trying to start Sample Tune and Develop Method in IntelliStart
  • Resetting from control menu does not resolve
  • Resetting EPC does not resolve
  • Found: Multiply Charged Parents is selected
  • Found: Molecular formula entered in the Parent Mass column

ENVIRONMENT

  • Xevo TQ-S
  • Xevo TQ-S micro
  • MassLynx 4.1
  • IntelliStart
  • Sample Tune and Develop Method (STDM)

CAUSE

The molecular formula was entered for the Parent Mass in the STDM setup. This field requires that the m/z be entered.

FIX or WORKAROUND

  1. If Multiply Charged Parents is required, specify the parent ion m/z as a numerical value.
  2. If Multiply Charged Parents is not required, disable this feature.

ADDITIONAL INFORMATION

The Multiply Charged Parents feature in STDM does not provide a place to specify the number of charges. You must specify the m/z on which the software will tune. Specifying the molecular formula provides only the molecular weight of the compound. With no entry for the number of charges, the m/z for a multiply charged parent ion is unknown and cannot be determined by the software.

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