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Inlet injects, but MS does not start. Error: Failed to start Mass Spectrometer acquisition and Waiting for Inject Start status - WKB11009

Article number: 11009

SYMPTOMS

  • Sample list analysis - inlet injects sample, but system does not start MS acquisition.
  • Inlet Method Error message:
    Failed to start Mass Spectrometer acquisition. Please ensure that the autosampler is correctly configured for contact start.
    clipboard_e12730af8a80eb310f1c2028301d2cc82.png
  • MassLynx says "Waiting for inject start".
  • Acquisition from Tune page starts correctly.

ENVIRONMENT

  • MassLynx
  • LC/MS
  • Symantec 12.1.6

CAUSE

Antivirus software not configured correctly - Network Threat Protection stopping the MS comms.

FIX or WORKAROUND

  1. Turn off Network Threat Protection.
  2. Configure antivirus to exclude all MassLynx processes and communications.

ADDITIONAL INFORMATION

See also article #1695: How to configure Symantec Antivirus software for MassLynx with screenshots

id11009, MLYNX, MLYNXV41, SUPMM

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