Can I run a Waters 2414 RI detector in W410 mode in Empower 3.8.0 or 3.8.0.1? - WKB269863

ENVIRONMENT

• Empower 3.8.0
• Empower 3.8.0.1
• 2414 Refractive Index Detector operating in W410 mode

ANSWER

As a result of a defect (CRI-6331) in Empower 3.8.0 and 3.8.0.1, running a Waters 2414 Refractive Index Detector in W410 mode results in an Instrument Failure message.

The Alliance 2414 SQT projects are configured to use the 2414 in emulate W410 mode, so the SQT cannot be used with these versions of Empower.

This defect (CRI-6331) resolved in Empower 3.8.0.2 and Empower 3.8.1

ADDITIONAL INFORMATION

From the Empower 3.8.0.2 Release Notes:

Previously, with the following system configurations, Empower 3.8.0 and Empower 3.8.0.1
software versions reported an instrument failure that prevented acquisition:

• Waters 2414 Refractive Index (RI) detector connected to an Alliance 2695 system running in
W410 emulate mode

Notes:
• This issue did not impact systems when the 2414 detector ran in native 2414 mode.

• The Alliance 2414 SQT (System Qualification Tool) projects were configured to use the
2414 detector in emulate W410 mode and, as a result, the SQT version could not be used
with Empower 3.8.0 and Empower 3.8.0.1.

• An Agilent 6890 GC system running without an Instrument Control Framework (ICF) Support
Layer

• Waters systems with an Alliance 2695 installed (and no other instruments installed in the
system)

Note: Systems that contain a module that uses an external instrument control software (ICS)
driver were not impacted, except for an Alliance HPLC Instrument, which uses a combination of
ICS and embedded drivers.

Upgrading to Empower 3.8.0.2 or Empower 3.8.1 software corrects the issue.