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How do I get my sample to retain to the reverse-phase SPE sorbent? - WKB196516

Article number: 196516

ENVIRONMENT

  • Solid-phase extraction (SPE)
  • Reverse phase
  • Oasis HLB
  • Oasis PRIME HLB
  • Sep-Pak C18

ANSWER

The sample will retain more effectively if loaded on less than 10% organic solvent.

ADDITIONAL INFORMATION

A high percentage of organic solvent in the load step will be more attractive to the sample than the sorbent, and the sample will not retain well.

For additional information, see What is the process for an SPE loading study? 

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