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What is the optimal flow rate range for a CORTECS 2.7 µm, 4.6 x 150 mm column on an Alliance e2695 HPLC system? - WKB110442

Article number: 110442

ENVIRONMENT

  • UltraPerformance Liquid Chromatography (UPLC)
  • Ultra High Performance Liquid Chromatography (UHPLC)
  • CORTECS columns

ANSWER

1.0 - 1.3 mL/min, depending on observed back pressure

ADDITIONAL INFORMATION

Waters has evaluated this flow rate range on an Alliance e2695 HPLC system with a TUV Detector.

The mobile phases used were 80:20 water/acetonitrile.

The column temperature was set to 30 °C.

Under these conditions, the total observed back pressures (column + system) were as follows:

At 1.0 mL/min = ~2,800 psi

At 1.3 mL/min = ~3,600 psi

NOTE: The total pressure may vary with the system used and how the system is configured.

CORTECS Columns Web page

CORTECS Solid Core Particle Columns Brochure

CORTECS Columns Infographic

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