How to prepare 0.5 mM sodium hydroxide solution in 90:10 IPA/water from powder or pellets - WKB81422

OBJECTIVE or GOAL

Prepare 0.5 mM sodium hydroxide solution in 90:10 IPA/water from powder or pellets (used in making calibration solution 0.5 mM sodium formate solution in 90:10 2-propanol/water)

ENVIRONMENT

• Preparing calibration solution
• IPA, isopropanol, 2-propanol or propan-2-ol
• Xevo QTof
• Xevo G2 QTof/Tof
• Xevo G2-S QTof/Tof
• Xevo G2-XS QTof/Tof
• SYNAPT
• SYNAPT G2-S
• SYNAPT G2-Si

PROCEDURE

1. Dissolve 200 mg of NaOH pellets in 1 L water and label "5 mM NaOH in water".
2. Transfer 10 mL of the 5 mM NaOH solution to a 100-mL volumetric flask.
3. Fill to the mark with 2-propanol (IPA).
4. Label the flask "0.5 mM sodium hydroxide solution in 90:10 IPA/water".

ADDITIONAL INFORMATION

SIGMA, > or equal to 98% pellets anhydrous

Acros organics sodium hydroxide micro pearls (99% purity)

Use only UPLC/MS-grade solvents