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MS peak area increasing injection to injection over run - WKB52784

Article number: 52784

SYMPTOMS

  • MS peak area increasing injection to injection over run.
  • Method dependent.
  • All ACQUITY diagnostics pass.
  • Refreshing sample, mobile phase, and column did not resolve issue.

ENVIRONMENT

  • XEVO TQ MS
  • MassLynx
  • Xevo TQD
  • Xevo TQ-S

CAUSE

Charging effect caused by a dirty ion block and guide.

FIX or WORKAROUND

  1. Clean ion block and guide following the appropriate Overview and Maintenance Guide.

ADDITIONAL INFORMATION

A dirty source enclosure can also cause this charging effect, so if cleaning the ion block, clean the source enclosure as well. 

eluent

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