- Xevo G2 is unable to calibrate in Resolution mode (residual mass increases with higher masses; see figure below)
- System resolution was checked with leucine enkephalin, and it was very good (around 35000)
- Xevo G2-XS
Low resolution when checked with GluFib.
FIX or WORKAROUND
- Adjust resolution on the system using System 1 & 2 settings (Reflectron grid, Steering, Tube lens, Pusher offset) to reach the highest possible resolution for GluFib.
- Calibrate the instrument.