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Retention time shift on an Acquity H-Class - WKB95183

Article number: 95183

SYMPTOMS

  • Retention time shift to the right
  • Peaks are co-eluting
  • Pressure drops from 12500psi to 10000psi
  • Replacing column and guard column does not help

ENVIRONMENT

  • ACQUITY UPLC H-Class

CAUSE

Leaking primary pump head

FIX or WORKAROUND

  1. Rebuild primary pump head

ADDITIONAL INFORMATION

For rebuild kit part numbers, see article What are the part numbers for ACQUITY pumphead rebuild kits? - WKB5426

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