ACQUITY: Poor sensitivity due to adsorption of the sample injection - WKB94591
Article number: 94591
SYMPTOMS
- Poor sensitivity due to adsorption of the sample injection
ENVIRONMENT
- LCT Premier XE
- UPLC
CAUSE
The sample is adsorbed on the needle and diffused by the “Pertial loop with needle over fill”.
FIX or WORKAROUND
- Check the “Pertial loop” from Inlet Method
ADDITIONAL INFORMATION
By switching to the Pertial loop, Weak wash solvent will be pushed up and this could prevent the diffusion.