Poor chromatographic peak shapes result in erratic data, poor accuracy and reproducibility - WKB6872
Article number: 6872
SYMPTOMS
- Poor chromatographic peak shape
- Inconsistent retention times
- Missing or no chromatographic peaks
- Erratic quantitative results; poor accuracy and precision
ENVIRONMENT
- ACQUITY UPLC
- ACQUITY UPLC Arc
- QuanLynx
- Empower
CAUSE
A degraded column/prefilter
FIX or WORKAROUND
- Replace prefilter (if present)
- Replace chromatographic column
ADDITIONAL INFORMATION
id6872, EMP2LIC, EMP2OPT, EMP2SW, EMP3GC, EMP3LIC, EMP3OPT, EMP3SW, EMPGC, EMPGPC, EMPLIC, EMPOWER2, EMPOWER3, EMPSW, SUP, UPAQSM, UPARBQSM, UPARBSMFTN, UPARCH30, UPARHQSM, UPARQSM, UPARSMFTN, UPBSMIVD, UPIBSMIVD, UPLCCOLHTR, UPNBINARY, UPPDAARCB, UPSMIVD, UPSMPMGR