Poor chromatographic peak shapes result in erratic data, poor accuracy and reproducibility - WKB6872
Article number: 6872
SYMPTOMS
- Poor chromatographic peak shape
- Inconsistent retention times
- Missing or no chromatographic peaks
- Erratic quantitative results; poor accuracy and precision
ENVIRONMENT
- ACQUITY UPLC
- ACQUITY UPLC Arc
- QuanLynx
- Empower
CAUSE
A degraded column/prefilter
FIX or WORKAROUND
- Replace prefilter (if present)
- Replace chromatographic column
ADDITIONAL INFORMATION
id6872, UPAQSM, UPARBQSM, UPARBSMFTN, UPARCH30, UPARHQSM, UPARQSM, UPARSMFTN, UPBINARY, UPPDAARCB