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Poor chromatographic peak shapes result in erratic data, poor accuracy and reproducibility - WKB6872

Article number: 6872

SYMPTOMS

  • Poor chromatographic peak shape
  • Inconsistent retention times
  • Missing or no chromatographic peaks
  • Erratic quantitative results; poor accuracy and precision

ENVIRONMENT

  • ACQUITY UPLC
  • ACQUITY UPLC Arc
  • QuanLynx
  • Empower

CAUSE

A degraded column/prefilter

FIX or WORKAROUND

  1. Replace prefilter (if present)
  2. Replace chromatographic column

ADDITIONAL INFORMATION

 

id6872, EMP2LIC, EMP2OPT, EMP2SW, EMP3GC, EMP3LIC, EMP3OPT, EMP3SW, EMPGC, EMPGPC, EMPLIC, EMPOWER2, EMPOWER3, EMPSW, SUP, UPAQSM, UPARBQSM, UPARBSMFTN, UPARCH30, UPARHQSM, UPARQSM, UPARSMFTN, UPBSMIVD, UPIBSMIVD, UPLCCOLHTR, UPNBINARY, UPPDAARCB, UPSMIVD, UPSMPMGR

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