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Waters

What can cause fronting peaks? - WKB5526

Article number: 5526

ENVIRONMENT

  • ACQUITY Arc
  • UPLC
  • HPLC

ANSWER

Excess dead volume from a fitting before the column that is not connected properly, leaving an unintended gap or space.

ADDITIONAL INFORMATION

 

Note the fronting at the beginning of the peak. It looks like the tailing that you might see at the end of a peak.

 

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