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Waters

System pressure far lower than expected - WKB49930

Article number: 49930

SYMPTOMS

  • Solvent manager pressure much lower than expected
  • Replacing check valve does not correct issue
  • Found: Retention times slightly later than expected
  • Found: Peak shape is not good
  • Found: Dynamic leak test failure: Accumulator leak rate >10,000 nL/min

ENVIRONMENT

  • ACQUITY UPLC H-Class
  • ACQUITY UPLC H-Class Quaternary Solvent Manager (QSM)

CAUSE

Bad high-pressure seal

FIX or WORKAROUND

Replace the high-pressure seal in the pump head.

ADDITIONAL INFORMATION

 

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