- Intermittently poor reproducibility (% RSD) based on peak area and height for an established customer method
- All system diagnostics pass
- System SQT precision tests pass
- ACQUITY UPLC H-Class
The use of methanol as sample diluent causes high variability with default sample manager settings.
FIX or WORKAROUND
Change the sample draw rate to 150 µL/min and add a 0.2-µL post-draw air gap.