- High %RSD for area counts
- No bubbles in sample syringe
- All ACQUITY Sample Manager- Fixed Loop diagnostics pass
- No leaks observed
- New column
- New standards
- Stable delta while flowing
- Partial Loop Needle Overfill (PLNO) injection method
- New needle, needle seal, and loop
- ACQUITY Sample Manager - Fixed Loop
- Faulty column stabilizer
FIX or WORKAROUND
- Perform replicate injections of known standard with an altered SM-FL method for full-loop injections.
- If full-loop injections pass %RSD, replace the column stabilizer (205000291 for 50- to 100-mm columns).