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Waters

Large, random pressure fluctuations - WKB45863

Article number: 45863

SYMPTOMS

  • Large, random pressure fluctuations
  • pressure drops during the end of the gradient.

ENVIRONMENT

  • Arc QSM-R
  • Alliance HPLC System
  • 2695 Separations Module
  • Gradient with phosphate buffer

CAUSE

Blocked inline filters/sinkers

FIX or WORKAROUND

Replace the inline filter (700002913) and sinkers (700010196).

Alliance 2695 inline filter = WAT0888084; solvent filter = WAT025531

ADDITIONAL INFORMATION

Suspect random cavitation

pressure ripple

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