Retention times are later than expected - WKB45384
Article number: 45384
SYMPTOMS
- Retention times are reproducible but later than expected
- Different methods give different but reproducible retention time shifts
ENVIRONMENT
- ACQUITY UPLC
- ACQUITY UPC2
- ACQUITY UPLC I-Class PLUS BSM
- ACQUITY UPLC BSM
CAUSE
A small leak at the outlet of the mixer
FIX or WORKAROUND
Tighten the connection or replace the tubing.
ADDITIONAL INFORMATION
The leak could be anywhere between the BSM and the column inlet.
If possible, run a dynamic leak test up to the column preheater, to confirm that the system is leak-tight.
id45384, DLT, UPBINARY, UPBINARY, UPBSM+, UPC2BSM, UPC2CMA, UPC2CNVMGR, UPC2SMFL, UPIBSM, UPIBSM, UPIBSM+, UPIBSM+, UPISMFL, UPISMFL+, UPISMFTIVD, UPISMFTN, UPISMFTN+, UPPBSM