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Retention times are later than expected - WKB45384

Article number: 45384

SYMPTOMS

  • Retention times are reproducible but later than expected
  • Different methods give different but reproducible retention time shifts

ENVIRONMENT

  • ACQUITY UPLC
  • ACQUITY UPC2

CAUSE

A small leak at the outlet of the mixer

FIX or WORKAROUND

Tighten the connection or replace the tubing.

ADDITIONAL INFORMATION

The leak could be anywhere between the BSM and the column inlet.

If possible, run a dynamic leak test up to the column preheater, to confirm that the system is leak-tight.

id45384, DLT, UPBINARY, UPC2BSM, UPC2CMA, UPC2CNVMGR, UPC2SMFL

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