System pressure drops midway through run on ACQUITY UPLC, and no peaks appear in chromatogram - WKB241907
Article number: 241907
SYMPTOMS
- System pressure drops midway through run, and no peaks appear in chromatogram
- Dynamic leak test passes for both pump A and pump B
ENVIRONMENT
- MassLynx
- ACQUITY UPLC BSM
- ACQUITY UPLC I-Class
- ACQUITY UPLC Sample Manager
- ACQUITY UPLC H-Class Quaternary Solvent Manager (QSM)
CAUSE
The mobile phase sinker and filters are blocked.
FIX or WORKAROUND
Replace the sinker and filters (see WKB1970).
ADDITIONAL INFORMATION
Solvent considerations for ACQUITY I-Class
id241907, A-30SDM, DLT, eluent, UPAQSM, UPBINARY, UPBSM+, UPIBSM, UPIBSM+, UPPBSM, UPPQSM, UPQSM, UPQSM, UPQSM+, UPQSM+, UPQSMBIO, UPQSMBIO, UPQSMBIO+, UPSMFTN, UPSMFTN+, UPSMFTNB+, UPSMFTNBIO