Pressure fluctuations on an ACQUITY UPLC BSM - WKB24137

SYMPTOMS

• Pressure fluctuations on pump B
• ACQUITY BSM pressure fluctuates despite no detected leaks  

ENVIRONMENT

• ACQUITY UPLC 
• ACQUITY UPLC BSM
• ACQUITY UPLC I-Class
• ACQUITY UPLC I-Class BSM

CAUSE

Faulty mixer

FIX or WORKAROUND

Replace the mixer

Check both aqueous and organic sides to ensure consistent pressure traces

ADDITIONAL INFORMATION

Due to higher compressibility, the issue is likely to be more prevalent on the aqueous side.  

Mixers available:

700005341 ASSY, MIXER, 50uL 18K

205000854 ASSY MIXER, 100uL 18K

700002911 ASSY MIXER, 50uL 15K

205000404 ASSY, MIXER, 100UL, ZIRCONIA 15K psi

205000403 ASSY, FILTER MIXER, 425UL, 10K PSI 

205000705 ACQUITY UPLC BSM, 380UL 15K PSI TFA MIXER