Retention time shift with ACQUITY H-Class QSM - WKB22815

SYMPTOMS

• Retention time shift

• Dynamic leak test failure when end point is inject pod outlet

• Strange pressure profiles across gradient

ENVIRONMENT

• ACQUITY UPLC H-Class QSM

• ACQUITY UPLC H-Class QSM Bio

CAUSE

Restriction in mixer and/or the tubing from vent valve to mixer

FIX or WORKAROUND

Replace the mixer.

ADDITIONAL INFORMATION

700005177 - ASSY, MIXER, 100µL, QSM (Default)

205000731 - ASSY, MIXER, 22µL, QSM

205000719 - ASSY, MIXER, 250µL, QSM

700005258 - ASSY, MIXER, 100µL, bioQSM