Skip to main content
Waters

System overpressure and visible leak on mixer inlet with ACQUITY UPLC I-Class BSM - WKB16216

Article number: 16216

SYMPTOMS

  • Pressure is higher than expected, even on a new column
  • System overpressures at low flow rates (<0.5 mL/min)
  • Retention time shifts
  • Visible leak on mixer inlet

ENVIRONMENT

  • ACQUITY UPLC
  • ACQUITY UPLC I-Class

CAUSE

Damaged or over-tightened tubing from the vent valve to the mixer

Clogged filter inside the mixer

FIX or WORKAROUND

  1. Replace the damaged tubing (link to ACQUITY UPLC BSM; link to ACQUITY UPLC I-Class BSM).
  2. Replace the mixer (link to ACQUITY UPLC BSM; link to ACQUITY UPLC I-Class BSM).
  3. Verify that the issue is resolved and that the system functions as expected.

ADDITIONAL INFORMATION

Not able to find a solution? Click here to request help.