Poor chromatography for polar compounds - WKB13726
Article number: 13726
SYMPTOMS
- Poor chromatography for 10% of samples (polar compounds only)
- Ok when transferred to backup instrument
ENVIRONMENT
- ACQUITY UPLC I-Class
CAUSE
Contamination of system
FIX or WORKAROUND
Flush I-Class with 80:10:10 IPA/H2O/FA, then 90:10 H2O/NH3, then IPA.
ADDITIONAL INFORMATION