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Waters

Poor chromatography for polar compounds - WKB13726

Article number: 13726

SYMPTOMS

  • Poor chromatography for 10% of samples (polar compounds only) 
  • Ok when transferred to backup instrument

ENVIRONMENT

  • ACQUITY UPLC I-Class

CAUSE

Contamination of system

FIX or WORKAROUND

Flush I-Class with  80:10:10 IPA/H2O/FA, then 90:10 H2O/NH3, then IPA.

ADDITIONAL INFORMATION

 

id13726, isopropanol, UPIBSM, UPIBSM+, UPISMFL, UPISMFL+, UPISMFTIVD, UPISMFTN, UPISMFTN+

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