What causes the GPV in a 2695 Separations Module to deteriorate in operation? - WKB124497

ENVIRONMENT

• 2695 Separations Module

ANSWER

• The solvent filter is removed to push the mobile phase with a syringe and speed up the prime.
• A solvent such as Hexafluoroisopropanol (HFIP) can damage the Teflon of the GPV valves.
• With halogens, because the chlorine corrodes metal, the valve may rust and break.
• The tube attached to the valve may loosen from vibration or other factors, and the liquid may leak and cause damage.
• A salt solvent concentration may crystallize when mixed with organic solvent.
• You want to run the salt solvent and leave it as is without washing.

The precautions are as follows:

• Do not use solvents such as those listed above.
• After running a salt solvent, wash with water, replace with organic solvent, and store.

ADDITIONAL INFORMATION