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How to disable Automatic Private IP Addressing (APIPA) - WKB5384

Article number: 5384


Disable APIPA for the Instrument network card (LAN) used by Waters instruments.

APIPA assigns a Class B IP address (from to, or 166.x.x.x) and default class B subnet mask ( when a DHCP server is either temporarily or permanently unavailable.


  • Microsoft Windows 7
  • Network connection
  • IPv4


  1. Browse to the registry editor (Start menu > type regedit > select regedit.exe)
  2. Navigate to HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet\Services\Tcpip\Parameters\Interfaces (This shows a line for each of the PC's network adapters.)
  3. Determine which is the Waters Instrument adapter by clicking on each one to display its information. Find the one that contains the IP addresses set when the PC was configured (for example, or  
  4. With this interface selected, click Edit > New > DWORD (32-bit) Value.
  5. Type or paste the name IPAutoconfigurationEnabled into the new key to change its name.
  6. Double-click the new key IPAutoconfigurationEnabled and ensure that a value of 0 (zero) appears. (A value of 1 enables autoconfiguration, a value of 0 disables it.)
  7.  Click OK and exit the registry editor.
  8. Restart the PC.

NOTE: Always consult local SOPs if modifying a registry value.  




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