System becomes unresponsive "waiting for inlet start" when using a column switch method or Pre-run/Post-run with MassLynx or OpenLynx - WKB15110

SYMPTOMS

• System using a column switching method or pre-run/post-run method prepares for analysis but then stops "waiting for inlet start"
• No error messages
• Inlet keeps pumping
• Stopping run and clicking reset communications clears system
• MassLynx runs from sample list with a method in "Inlet Switch" column
• OpenLynx / OAlogin method requires a switch method before running a sample
• MassLynx or OpenLynx using pre-run and post-run methods

ENVIRONMENT

• MassLynx
• ACQUITY Column Manager on ICS 1.50 and 1.51
• SQD2 and Xevo TQD
• Xevo G2 Tof and Xevo G2 QTof
• SQD
• XEVO TQ and XEVO TQ-S
• ACQUITY QDa Mass Detector
• Xevo TQ-S
• Xevo TQ-MS
• ACQUITY Arc

CAUSE

Bug in the software causes the switch methods and pre-run and post-run methods not to work - CRI-5831

The method loads but the pump runs indefinitely and the analysis does not progress.
This occurs with combinations of MassLynx software version and ICS version (1.50 and 1.51 and others)

FIX or WORKAROUND

• Fixed in SCN 1046 and subsequent SCNs for all currently supported Quadrupole instruments

See article #554, What is the latest version of MassLynx SCN that supports my MS instrument? 

ADDITIONAL INFORMATION

This same bug affects inlet pre-run and post-run methods.

• Historical fixes:
• ACQUITY QDa - fixed in SCN 993, except for ACQUITY Arc
• SQD2 and Xevo TQD - fixed in SCN 855 and subsequent software except for ACQUITY Arc
• SQD - fixed in SCN 877 and subsequent software
• XEVO TQ and XEVO TQ-S - fixed in SCN 878 with SCN 843 and subsequent software
• Xevo G2 Tof and Xevo G2 QTof - fixed in SCN 869 and subsequent software